Betis has been playing consistently this season, sitting in the top half of the table. However, the team is playing its home game at the Estadio de la Cartuja, depriving it of its usual home advantage. In recent games, the team has shown a lackluster defense, conceding goals even in successful matches.
Atlético Madrid has a better squad and is higher in the standings. Despite their recent defeat to Arsenal in the Champions League, the team looks extremely confident in the league, especially in attack. Motivation will be extremely high after their European defeat.
Given Atlético's superior quality, their motivation, and Betis's lack of a true home advantage, a victory for the visitors seems most likely.