Twente are in good form, having made a confident start to the Eredivisie and Champions League. They have been prolific, scoring 10 goals in their last four matches, and look formidable in attack, especially at home.
Chelsea are traditionally one of the leaders in European football, but this season they have shown some defensive inconsistency. They have conceded in three of their last five matches, highlighting the vulnerability of their defensive structure.
Given Twente's attacking potential and Chelsea's defensive problems, a goal for the home team seems likely. However, the quality of the visitors suggests they will score a goal in return.